Blood Type O Most Protected From Malaria, Blood Type A The Worst

Once again there is a study out showing people with blood type O ranking the best for overall protection while blood type A people rate the poorest.


Blood type O conveys protection against malaria because RIFIN, a protein secreted by parasites, bonds weakly with type O blood cells while strongly linking to type A.

Source: Goel S, Palmkvist M, Moll K, et al. RIFINs are Adhesins Implicated in Severe Plasmodium falciparum Malaria. Nature Medicine. 2015.

Once again the question pops up who mosquitoes are more likely to bite than others. Type O is the usual reply and though correct, more and more factors are being added at least as high possibilities in terms of significance.

Composition of Human Skin Microbiota Affects Attractiveness to Malaria Mosquitoes


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