Malaria

Blood type O conveys protection against malaria because RIFIN, a protein secreted by parasites, bonds weakly with type O blood cells while strongly linking to type A.
malaria
Source: Goel S, Palmkvist M, Moll K, et al. RIFINs are Adhesins Implicated in Severe Plasmodium falciparum Malaria. Nature Medicine. 2015.

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