{"id":160,"date":"2014-12-14T09:32:48","date_gmt":"2014-12-14T09:32:48","guid":{"rendered":"http:\/\/www.rhesusnegative.net\/staynegative\/?page_id=160"},"modified":"2018-07-26T04:27:16","modified_gmt":"2018-07-26T04:27:16","slug":"what-is-bombay-blood","status":"publish","type":"page","link":"https:\/\/www.rhesusnegative.net\/staynegative\/popular-questions\/what-is-bombay-blood\/","title":{"rendered":"What is Bombay Blood?"},"content":{"rendered":"<div style=\"padding-bottom:20px; padding-top:10px;\" class=\"hupso-share-buttons\"><!-- Hupso Share Buttons - https:\/\/www.hupso.com\/share\/ --><a class=\"hupso_toolbar\" href=\"https:\/\/www.hupso.com\/share\/\"><img data-recalc-dims=\"1\" decoding=\"async\" src=\"https:\/\/i0.wp.com\/static.hupso.com\/share\/buttons\/share-medium.png?w=640&#038;ssl=1\" style=\"border:0px; padding-top:5px; float:left;\" alt=\"Share Button\"\/><\/a><script type=\"text\/javascript\">var hupso_services_t=new Array(\"Twitter\",\"Facebook\",\"Pinterest\",\"Linkedin\");var hupso_background_t=\"#EAF4FF\";var hupso_border_t=\"#66CCFF\";var hupso_toolbar_size_t=\"medium\";var hupso_twitter_via = \"datebytype\";var hupso_image_folder_url = \"\";var hupso_twitter_via=\"datebytype\";var hupso_url_t=\"\";var hupso_title_t=\"What is Bombay Blood?\";<\/script><script type=\"text\/javascript\" src=\"https:\/\/static.hupso.com\/share\/js\/share_toolbar.js\"><\/script><!-- Hupso Share Buttons --><\/div><p><b>What is the Bombay blood group?<\/b><\/p>\n<p>Bombay blood group is a type of <a href=\"http:\/\/www.thehealthsite.com\/topics\/blood-group\/\">blood group<\/a> that has no \u2018H\u2019 antigen. People usually have either of A, B, AB or O blood groups hich have H antigens.\u00a0For example, a person with A blood group will have type A antigens and anti B antibodies (immune cells that fight against antigens other than their own antigens, in this case they produce antibodies against B). Apart from A, B and O blood group, we also have\u00a0an antigen known as\u00a0H antigen.<\/p>\n<p>However, people with Bombay blood group do not have a H antigen meaning they have anti-a, anti-B and anti-H antibodies in their blood. So transfusion of blood from people with blood group A, B, AB or O (which contains H antigens) will cause a reaction\u00a0(acute haemolytic transfusion reaction) in the body leading to serious health complications. (Read:\u00a0<a href=\"http:\/\/www.thehealthsite.com\/diseases-conditions\/mangalore-docs-perform-open-heart-surgery-on-woman-with-rare-blood-group\/\">Mangalore docs perform open heart surgery on woman with rare blood group<\/a>)<\/p>\n<p>The origin of Bombay blood has yet to be determined. But there are a few places and populations among whom the frequencies are unusually high:<\/p>\n<blockquote><p>High incidence of Bombay phenotype reported in Orissa of eastern India, among Kutia Kondh tribe [2]. Another study from northwestern Orissa reported an average of 1 in 278 Bombay phenotype among Bhuyan tribal population [3].<\/p><\/blockquote>\n<p>Source: <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4115078\/\" rel=\"noopener\" target=\"_blank\">Prevalence of Bombay Group Blood in Southern Bengal Population<\/a><br \/>\nAnd here:<br \/>\n<figure id=\"attachment_3599\" aria-describedby=\"caption-attachment-3599\" style=\"width: 701px\" class=\"wp-caption alignnone\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" src=\"https:\/\/i0.wp.com\/www.rhesusnegative.net\/staynegative\/wp-content\/uploads\/2018\/07\/Bombay-blood-reunion.gif?resize=640%2C880\" alt=\"\" width=\"640\" height=\"880\" class=\"size-full wp-image-3599\" \/><figcaption id=\"caption-attachment-3599\" class=\"wp-caption-text\">On the island of Reunion, the frequency of Bombay blood is unusually high as well.<br \/><\/figcaption><\/figure><\/p>\n<blockquote><p>Forty-two H-deficient individuals (lacking H antigen on erythrocytes) with anti-H in their sera were found on Reunion Island. A, B, and AB Bombay subjects had small but detectable amounts of A and\/or B antigens on erythrocytes. All the H-deficient phenotypes tested were nonsecretors of ABH in their saliva, and one-third were Lewis negative. Fifty-three of the 108 (49%) unaffected members in the 14 Bombay pedigrees analyzed were se\/se, showing that the families were selected for the nonsecretor trait, and suggesting that the Bombay probands used to select the families have se\/se genotype. In accordance with this concept, all the children from Bombay nonsecretor x unaffected nonsecretor matings were se\/se. Segregation of H and Se is compatible with the genetic model proposing that Se and H are closely linked structural genes, and the analysis of the present and previously published Bombay pedigrees strongly supports this model.<\/p><\/blockquote>\n<p>Source: <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC1685705\/\" rel=\"noopener\" target=\"_blank\">H-deficient blood groups ( Bombay) of Reunion Island.<\/a><br \/>\n<em>Thank you to Gordon Scherer for bringing the later to my attention.<\/em><\/p>\n<p>If you are in need of Bombay blood, contact these guys through Facebook:<\/p>\n<p><a href=\"https:\/\/www.facebook.com\/groups\/bombaybloodgroup\/\" target=\"_blank\">Bombay Blood Group<\/a><\/p>\n<div style=\"padding-bottom:20px; padding-top:10px;\" class=\"hupso-share-buttons\"><!-- Hupso Share Buttons - https:\/\/www.hupso.com\/share\/ --><a class=\"hupso_toolbar\" href=\"https:\/\/www.hupso.com\/share\/\"><img data-recalc-dims=\"1\" decoding=\"async\" src=\"https:\/\/i0.wp.com\/static.hupso.com\/share\/buttons\/share-medium.png?w=640&#038;ssl=1\" style=\"border:0px; padding-top:5px; float:left;\" alt=\"Share Button\"\/><\/a><script type=\"text\/javascript\">var hupso_services_t=new Array(\"Twitter\",\"Facebook\",\"Pinterest\",\"Linkedin\");var hupso_background_t=\"#EAF4FF\";var hupso_border_t=\"#66CCFF\";var hupso_toolbar_size_t=\"medium\";var hupso_twitter_via = \"datebytype\";var hupso_image_folder_url = \"\";var hupso_twitter_via=\"datebytype\";var hupso_url_t=\"\";var hupso_title_t=\"What is Bombay Blood?\";<\/script><script type=\"text\/javascript\" src=\"https:\/\/static.hupso.com\/share\/js\/share_toolbar.js\"><\/script><!-- Hupso Share Buttons --><\/div>","protected":false},"excerpt":{"rendered":"<div style=\"padding-bottom:20px; padding-top:10px;\" class=\"hupso-share-buttons\"><!-- Hupso Share Buttons - https:\/\/www.hupso.com\/share\/ --><a class=\"hupso_toolbar\" href=\"https:\/\/www.hupso.com\/share\/\"><img src=\"https:\/\/static.hupso.com\/share\/buttons\/share-medium.png\" style=\"border:0px; padding-top:5px; float:left;\" alt=\"Share Button\"\/><\/a><script type=\"text\/javascript\">var hupso_services_t=new Array(\"Twitter\",\"Facebook\",\"Pinterest\",\"Linkedin\");var hupso_background_t=\"#EAF4FF\";var hupso_border_t=\"#66CCFF\";var hupso_toolbar_size_t=\"medium\";var hupso_twitter_via = \"datebytype\";var hupso_image_folder_url = \"\";var hupso_twitter_via=\"datebytype\";var hupso_url_t=\"\";var hupso_title_t=\"What is Bombay Blood?\";<\/script><script type=\"text\/javascript\" src=\"https:\/\/static.hupso.com\/share\/js\/share_toolbar.js\"><\/script><!-- Hupso Share Buttons --><\/div>What is the Bombay blood group? Bombay blood group is a type of blood group that has no \u2018H\u2019 antigen. People usually have either of A, B, AB or O blood groups hich have H antigens.\u00a0For example, a person with A blood group will have type A antigens and anti B antibodies (immune cells that fight against antigens other than their own antigens, in this case they produce antibodies against B). Apart from A, B and O blood group, we also have\u00a0an antigen known as\u00a0H antigen. However, people with Bombay blood group do not have a H antigen meaning they have anti-a, anti-B and anti-H antibodies in their blood. So transfusion of blood from people with blood group A, B, <div style=\"padding-bottom:20px; padding-top:10px;\" class=\"hupso-share-buttons\"><!-- Hupso Share Buttons - https:\/\/www.hupso.com\/share\/ --><a class=\"hupso_toolbar\" href=\"https:\/\/www.hupso.com\/share\/\"><img src=\"https:\/\/static.hupso.com\/share\/buttons\/share-medium.png\" style=\"border:0px; padding-top:5px; float:left;\" alt=\"Share Button\"\/><\/a><script type=\"text\/javascript\">var hupso_services_t=new Array(\"Twitter\",\"Facebook\",\"Pinterest\",\"Linkedin\");var hupso_background_t=\"#EAF4FF\";var hupso_border_t=\"#66CCFF\";var hupso_toolbar_size_t=\"medium\";var hupso_twitter_via = \"datebytype\";var hupso_image_folder_url = \"\";var hupso_twitter_via=\"datebytype\";var hupso_url_t=\"\";var hupso_title_t=\"What is Bombay Blood?\";<\/script><script type=\"text\/javascript\" src=\"https:\/\/static.hupso.com\/share\/js\/share_toolbar.js\"><\/script><!-- Hupso Share Buttons --><\/div>","protected":false},"author":1,"featured_media":998,"parent":29,"menu_order":0,"comment_status":"open","ping_status":"open","template":"","meta":{"jetpack_post_was_ever_published":false,"amp_status":"","footnotes":""},"class_list":["post-160","page","type-page","status-publish","has-post-thumbnail","hentry"],"jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/P5DV68-2A","_links":{"self":[{"href":"https:\/\/www.rhesusnegative.net\/staynegative\/wp-json\/wp\/v2\/pages\/160","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.rhesusnegative.net\/staynegative\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.rhesusnegative.net\/staynegative\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.rhesusnegative.net\/staynegative\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.rhesusnegative.net\/staynegative\/wp-json\/wp\/v2\/comments?post=160"}],"version-history":[{"count":4,"href":"https:\/\/www.rhesusnegative.net\/staynegative\/wp-json\/wp\/v2\/pages\/160\/revisions"}],"predecessor-version":[{"id":3600,"href":"https:\/\/www.rhesusnegative.net\/staynegative\/wp-json\/wp\/v2\/pages\/160\/revisions\/3600"}],"up":[{"embeddable":true,"href":"https:\/\/www.rhesusnegative.net\/staynegative\/wp-json\/wp\/v2\/pages\/29"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.rhesusnegative.net\/staynegative\/wp-json\/wp\/v2\/media\/998"}],"wp:attachment":[{"href":"https:\/\/www.rhesusnegative.net\/staynegative\/wp-json\/wp\/v2\/media?parent=160"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}