{"id":6086,"date":"2020-01-09T03:47:26","date_gmt":"2020-01-09T03:47:26","guid":{"rendered":"https:\/\/www.rhesusnegative.net\/staynegative\/?p=6086"},"modified":"2020-01-09T03:49:26","modified_gmt":"2020-01-09T03:49:26","slug":"can-a-blood-type-ab-o-couple-have-ab-and-o-children","status":"publish","type":"post","link":"https:\/\/www.rhesusnegative.net\/staynegative\/can-a-blood-type-ab-o-couple-have-ab-and-o-children\/","title":{"rendered":"Can a blood type AB\/O couple have AB and O children?"},"content":{"rendered":"<div style=\"padding-bottom:20px; padding-top:10px;\" class=\"hupso-share-buttons\"><!-- Hupso Share Buttons - https:\/\/www.hupso.com\/share\/ --><a class=\"hupso_toolbar\" href=\"https:\/\/www.hupso.com\/share\/\"><img data-recalc-dims=\"1\" decoding=\"async\" src=\"https:\/\/i0.wp.com\/static.hupso.com\/share\/buttons\/share-medium.png?w=640&#038;ssl=1\" style=\"border:0px; padding-top:5px; float:left;\" alt=\"Share Button\"\/><\/a><script type=\"text\/javascript\">var hupso_services_t=new Array(\"Twitter\",\"Facebook\",\"Pinterest\",\"Linkedin\");var hupso_background_t=\"#EAF4FF\";var hupso_border_t=\"#66CCFF\";var hupso_toolbar_size_t=\"medium\";var hupso_twitter_via = \"datebytype\";var hupso_image_folder_url = \"\";var hupso_twitter_via=\"datebytype\";var hupso_url_t=\"\";var hupso_title_t=\"Can a blood type AB\/O couple have AB and O children?\";<\/script><script type=\"text\/javascript\" src=\"https:\/\/static.hupso.com\/share\/js\/share_toolbar.js\"><\/script><!-- Hupso Share Buttons --><\/div>\n<p>The claim that blood type AB people cannot have blood type O offspring and vice versa is false.<\/p>\n\n\n\n<div class=\"wp-block-image\"><figure class=\"aligncenter\"><img decoding=\"async\" src=\"https:\/\/i1.wp.com\/www.datebytype.com\/bloodtypedating\/wp-content\/uploads\/2017\/11\/cisab.jpg?resize=300%2C225\" alt=\"\"\/><figcaption> There is a phenomenon called cisAB where both, the A and the B are encoded into one allele.<br>So if for example you are cisAB\/O, partnering with a blood type O can result in offspring being either cisAB\/O with phenotype AB or blood type O. <br> Because both A2 and B3 phenotypes are inherited as the single unit in the cis manner, it was named as cis-AB allele.<br><br> <\/figcaption><\/figure><\/div>\n\n\n\n<p><strong>In detail:<\/strong><\/p>\n\n\n\n<p>When one parent carries a Cis AB allele, the other allele can be any of O, A or B and the phenotype of this parent is always AB, but the children will inherit either the AB or the other allele from this parent.<\/p>\n\n\n\n<ol class=\"wp-block-list\"><li>If the other parent is O phenotype (OO genotype) there are three possible scenarios for the blood group of children of a Cis AB carrier (and a 4th very unlikely scenario):<ol><li>The second allele is O: children are either&nbsp;<strong>AB<\/strong>&nbsp;or&nbsp;<strong>O<\/strong><\/li><li>Second allele is A: Children are either&nbsp;<strong>AB<\/strong>&nbsp;or A<\/li><li>Second allele is B: Children are either&nbsp;<strong>AB<\/strong>&nbsp;or B<\/li><li>A very rare 4th possibility exists: if the other allele is also Cis AB then the children will be always AB irrespective whatever the other parent is, because they will have one cis AB allele from this parent.<\/li><\/ol><\/li><li>If the other parent is type A, depending on whether this parent is genotypically AA or AO and what the other allele is in the Cis Ab carrying parent, the following scenarios are possible:<ol><li>Other parent is AO and second allele is O: The children are either AB or A or&nbsp;<strong>O<\/strong><\/li><li>Other parent is AA and the second allele is O: The children are either AB or A<\/li><li>Other parent is AO and second allele is A: The children are either AB or A<\/li><li>Other parent is AA and the second allele is A: The children are either AB or A<\/li><li>Other parent is AO and the second allele is B: The children are either AB or B<\/li><li>Other parent is AA and the second allele is B: The children are always AB<\/li><li>Rare situation: If the other allele is also cis AB:The children are always AB<\/li><\/ol><\/li><li>Likewise, there will be similar scenarios for the other parent being type B:<ol><li>Other parent is BO and second allele is O: The children are either AB or B or&nbsp;<strong>O<\/strong><\/li><li>Other parent is BO and second allele is A: The children are either AB or A<\/li><li>Other parent is BO and the second allele is B: The children are always AB or B<\/li><li>Other parent is BB and the second allele is B: The children are either AB or B<\/li><li>Other parent is BB and the second allele is O: The children are either AB or B<\/li><li>Other parent is BB and the second allele is A: The children are always AB<\/li><li>Rare situation: If the other allele is also cis AB:The children are always AB<\/li><\/ol><\/li><\/ol>\n\n\n\n<p>(<em>Caution: ABO inheritance is generally derived assuming the children are not the very rare&nbsp;<a href=\"https:\/\/en.wikipedia.org\/wiki\/Hh_antigen_system\">Bombay phenotype<\/a>&nbsp;which would require both parents to be carriers of it.<\/em>)<\/p>\n\n\n\n<p><strong>So don\u2019t freak out if you are blood type O and your dad is AB. Years ago every doctor would have claimed that it is impossible, but now we know it isn\u2019t.<\/strong><\/p>\n\n\n\n<p>Blood types are simply not reliable ways to exclude paternity in general. More reasons here:<br><a href=\"http:\/\/www.rhesusnegative.net\/staynegative\/4-major-reasons-blood-type-tests-can-show-different-results\/\" rel=\"noreferrer noopener\" target=\"_blank\">4 major reasons why blood type tests can show different results<\/a><ins><\/ins><\/p>\n<div style=\"padding-bottom:20px; padding-top:10px;\" class=\"hupso-share-buttons\"><!-- Hupso Share Buttons - https:\/\/www.hupso.com\/share\/ --><a class=\"hupso_toolbar\" href=\"https:\/\/www.hupso.com\/share\/\"><img data-recalc-dims=\"1\" decoding=\"async\" src=\"https:\/\/i0.wp.com\/static.hupso.com\/share\/buttons\/share-medium.png?w=640&#038;ssl=1\" style=\"border:0px; padding-top:5px; float:left;\" alt=\"Share Button\"\/><\/a><script type=\"text\/javascript\">var hupso_services_t=new Array(\"Twitter\",\"Facebook\",\"Pinterest\",\"Linkedin\");var hupso_background_t=\"#EAF4FF\";var hupso_border_t=\"#66CCFF\";var hupso_toolbar_size_t=\"medium\";var hupso_twitter_via = \"datebytype\";var hupso_image_folder_url = \"\";var hupso_twitter_via=\"datebytype\";var hupso_url_t=\"\";var hupso_title_t=\"Can a blood type AB\/O couple have AB and O children?\";<\/script><script type=\"text\/javascript\" src=\"https:\/\/static.hupso.com\/share\/js\/share_toolbar.js\"><\/script><!-- Hupso Share Buttons --><\/div>","protected":false},"excerpt":{"rendered":"<div style=\"padding-bottom:20px; padding-top:10px;\" class=\"hupso-share-buttons\"><!-- Hupso Share Buttons - https:\/\/www.hupso.com\/share\/ --><a class=\"hupso_toolbar\" href=\"https:\/\/www.hupso.com\/share\/\"><img src=\"https:\/\/static.hupso.com\/share\/buttons\/share-medium.png\" style=\"border:0px; padding-top:5px; float:left;\" alt=\"Share Button\"\/><\/a><script type=\"text\/javascript\">var hupso_services_t=new Array(\"Twitter\",\"Facebook\",\"Pinterest\",\"Linkedin\");var hupso_background_t=\"#EAF4FF\";var hupso_border_t=\"#66CCFF\";var hupso_toolbar_size_t=\"medium\";var hupso_twitter_via = \"datebytype\";var hupso_image_folder_url = \"\";var hupso_twitter_via=\"datebytype\";var hupso_url_t=\"\";var hupso_title_t=\"Can a blood type AB\/O couple have AB and O children?\";<\/script><script type=\"text\/javascript\" src=\"https:\/\/static.hupso.com\/share\/js\/share_toolbar.js\"><\/script><!-- Hupso Share Buttons --><\/div>The claim that blood type AB people cannot have blood type O offspring and vice versa is false. In detail: When one parent carries a Cis AB allele, the other allele can be any of O, A or B and the phenotype of this parent is always AB, but the children will inherit either the AB or the other allele from this parent. If the other parent is O phenotype (OO genotype) there are three possible scenarios for the blood group of children of a Cis AB carrier (and a 4th very unlikely scenario): The second allele is O: children are either&nbsp;AB&nbsp;or&nbsp;O Second allele is A: Children are either&nbsp;AB&nbsp;or A Second allele is B: Children are either&nbsp;AB&nbsp;or B A very <div style=\"padding-bottom:20px; padding-top:10px;\" class=\"hupso-share-buttons\"><!-- Hupso Share Buttons - https:\/\/www.hupso.com\/share\/ --><a class=\"hupso_toolbar\" href=\"https:\/\/www.hupso.com\/share\/\"><img src=\"https:\/\/static.hupso.com\/share\/buttons\/share-medium.png\" style=\"border:0px; padding-top:5px; float:left;\" alt=\"Share Button\"\/><\/a><script type=\"text\/javascript\">var hupso_services_t=new Array(\"Twitter\",\"Facebook\",\"Pinterest\",\"Linkedin\");var hupso_background_t=\"#EAF4FF\";var hupso_border_t=\"#66CCFF\";var hupso_toolbar_size_t=\"medium\";var hupso_twitter_via = \"datebytype\";var hupso_image_folder_url = \"\";var hupso_twitter_via=\"datebytype\";var hupso_url_t=\"\";var hupso_title_t=\"Can a blood type AB\/O couple have AB and O children?\";<\/script><script type=\"text\/javascript\" src=\"https:\/\/static.hupso.com\/share\/js\/share_toolbar.js\"><\/script><!-- Hupso Share Buttons --><\/div>","protected":false},"author":1,"featured_media":6088,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"amp_status":"","_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","enabled":false},"version":2}},"categories":[1],"tags":[],"class_list":["post-6086","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-facts"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"https:\/\/i0.wp.com\/www.rhesusnegative.net\/staynegative\/wp-content\/uploads\/2020\/01\/cisab.jpg?fit=300%2C225&ssl=1","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p5DV68-1Aa","_links":{"self":[{"href":"https:\/\/www.rhesusnegative.net\/staynegative\/wp-json\/wp\/v2\/posts\/6086","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.rhesusnegative.net\/staynegative\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.rhesusnegative.net\/staynegative\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.rhesusnegative.net\/staynegative\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.rhesusnegative.net\/staynegative\/wp-json\/wp\/v2\/comments?post=6086"}],"version-history":[{"count":2,"href":"https:\/\/www.rhesusnegative.net\/staynegative\/wp-json\/wp\/v2\/posts\/6086\/revisions"}],"predecessor-version":[{"id":6089,"href":"https:\/\/www.rhesusnegative.net\/staynegative\/wp-json\/wp\/v2\/posts\/6086\/revisions\/6089"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.rhesusnegative.net\/staynegative\/wp-json\/wp\/v2\/media\/6088"}],"wp:attachment":[{"href":"https:\/\/www.rhesusnegative.net\/staynegative\/wp-json\/wp\/v2\/media?parent=6086"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.rhesusnegative.net\/staynegative\/wp-json\/wp\/v2\/categories?post=6086"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.rhesusnegative.net\/staynegative\/wp-json\/wp\/v2\/tags?post=6086"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}