{"id":7470,"date":"2020-04-19T05:53:38","date_gmt":"2020-04-19T05:53:38","guid":{"rendered":"https:\/\/www.rhesusnegative.net\/staynegative\/?p=7470"},"modified":"2020-04-19T05:53:47","modified_gmt":"2020-04-19T05:53:47","slug":"can-plasma-from-covid-19-survivors-treat-others","status":"publish","type":"post","link":"https:\/\/www.rhesusnegative.net\/staynegative\/can-plasma-from-covid-19-survivors-treat-others\/","title":{"rendered":"Can plasma from COVID-19 survivors treat others?"},"content":{"rendered":"<div style=\"padding-bottom:20px; padding-top:10px;\" class=\"hupso-share-buttons\"><!-- Hupso Share Buttons - https:\/\/www.hupso.com\/share\/ --><a class=\"hupso_toolbar\" href=\"https:\/\/www.hupso.com\/share\/\"><img data-recalc-dims=\"1\" decoding=\"async\" src=\"https:\/\/i0.wp.com\/static.hupso.com\/share\/buttons\/share-medium.png?w=640&#038;ssl=1\" style=\"border:0px; padding-top:5px; float:left;\" alt=\"Share Button\"\/><\/a><script type=\"text\/javascript\">var hupso_services_t=new Array(\"Twitter\",\"Facebook\",\"Pinterest\",\"Linkedin\");var hupso_background_t=\"#EAF4FF\";var hupso_border_t=\"#66CCFF\";var hupso_toolbar_size_t=\"medium\";var hupso_twitter_via = \"datebytype\";var hupso_image_folder_url = \"\";var hupso_twitter_via=\"datebytype\";var hupso_url_t=\"\";var hupso_title_t=\"Can plasma from COVID-19 survivors treat others?\";<\/script><script type=\"text\/javascript\" src=\"https:\/\/static.hupso.com\/share\/js\/share_toolbar.js\"><\/script><!-- Hupso Share Buttons --><\/div>\n<div class=\"wp-block-image\"><figure class=\"aligncenter\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" width=\"640\" height=\"368\" src=\"https:\/\/i0.wp.com\/www.rhesusnegative.net\/staynegative\/wp-content\/uploads\/2020\/04\/EV2HyHAWkAocACA.jpg?resize=640%2C368&#038;ssl=1\" alt=\"\" class=\"wp-image-7471\" srcset=\"https:\/\/i0.wp.com\/www.rhesusnegative.net\/staynegative\/wp-content\/uploads\/2020\/04\/EV2HyHAWkAocACA.jpg?w=679&amp;ssl=1 679w, https:\/\/i0.wp.com\/www.rhesusnegative.net\/staynegative\/wp-content\/uploads\/2020\/04\/EV2HyHAWkAocACA.jpg?resize=300%2C172&amp;ssl=1 300w\" sizes=\"auto, (max-width: 640px) 100vw, 640px\" \/><figcaption> <strong>What is Plasma?<\/strong><br>Plasma is the clear,&nbsp;<strong>yellowish liquid<\/strong>&nbsp;component of the blood. It carries cells and proteins throughout the body. It makes up about<strong>&nbsp;55% of the body&#8217;s total blood volume<\/strong><br>Blood serum is blood plasma without clotting factors. <\/figcaption><\/figure><\/div>\n\n\n\n<p><strong>This question has come up a lot lately. Is hyperimmune plasma therapy effective?<\/strong><\/p>\n\n\n\n<p>Hyperimmune serum is blood plasma containing high amounts of an antibody. It has been hypothesised that hyperimmune serum may be an effective therapy for persons infected with the Ebola virus.<\/p>\n\n\n\n<figure class=\"wp-block-image\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" width=\"564\" height=\"423\" src=\"https:\/\/i0.wp.com\/www.rhesusnegative.net\/staynegative\/wp-content\/uploads\/2018\/08\/a2ac9174ee9f5b371f90edee0fe23ceb.jpg?resize=564%2C423&#038;ssl=1\" alt=\"\" class=\"wp-image-3664\" srcset=\"https:\/\/i0.wp.com\/www.rhesusnegative.net\/staynegative\/wp-content\/uploads\/2018\/08\/a2ac9174ee9f5b371f90edee0fe23ceb.jpg?w=564&amp;ssl=1 564w, https:\/\/i0.wp.com\/www.rhesusnegative.net\/staynegative\/wp-content\/uploads\/2018\/08\/a2ac9174ee9f5b371f90edee0fe23ceb.jpg?resize=300%2C225&amp;ssl=1 300w\" sizes=\"auto, (max-width: 564px) 100vw, 564px\" \/><\/figure>\n\n\n\n<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4264590\/?report=reader\">Another study<\/a>  identified 32 studies of <strong>SARS coronavirus infection<\/strong> and severe influenza and concluded the following:<\/p>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\"><p>Available evidence suggests that convalescent plasma is <strong>likely to reduce mortality<\/strong> during SARIs of viral etiology, with larger treatment effects if it commenced early after symptom onset. However, this is based on predominately low-quality, uncontrolled studies. Our review <strong>supports the use of&nbsp; convalescent plasma in critically ill MERS-CoV\u2013infected patients<\/strong> as part of a well-designed clinical trial or other formal evaluation. <\/p><\/blockquote>\n\n\n\n<p><strong>Here is a current project in Santiago, Chile:<\/strong><\/p>\n\n\n\n<figure class=\"wp-block-embed-twitter wp-block-embed is-type-rich is-provider-twitter\"><div class=\"wp-block-embed__wrapper\">\n<blockquote class=\"twitter-tweet\" data-width=\"550\" data-dnt=\"true\"><p lang=\"es\" dir=\"ltr\">Hoy hicimos nuestra primera terapia con plasma hiperinmune de pacientes convalecientes intentando derrotar a la <a href=\"https:\/\/twitter.com\/hashtag\/COVID19?src=hash&amp;ref_src=twsrc%5Etfw\">#COVID19<\/a> <a href=\"https:\/\/t.co\/eRSLYRYiDJ\">pic.twitter.com\/eRSLYRYiDJ<\/a><\/p>&mdash; SEBASTIAN UGARTE (@sebasugarte) <a href=\"https:\/\/twitter.com\/sebasugarte\/status\/1251305575377522689?ref_src=twsrc%5Etfw\">April 18, 2020<\/a><\/blockquote><script async src=\"https:\/\/platform.twitter.com\/widgets.js\" charset=\"utf-8\"><\/script>\n<\/div><\/figure>\n\n\n\n<p>He also states in a reply that he only uses this therapy on critically ill patients only.<\/p>\n\n\n\n<p><em>From  <\/em><strong><em>STUDY IQ<\/em><\/strong><em>:<\/em><\/p>\n\n\n\n<p><strong>\u2018Convalescent\u2019 Plasma Therapy<\/strong><\/p>\n\n\n\n<p><strong>Convalescent = recovering from an illness or medical treatment.<\/strong><\/p>\n\n\n\n<p>\u2022 When people get sick with a virus or bacteria, they recover from the illness because their body produces antibodies specifically to fight that&nbsp;<strong>\u2018ANTIGEN\u2019<\/strong><\/p>\n\n\n\n<p>\u2022 Vaccines also spur the body into producing these protective antibodies.<\/p>\n\n\n\n<p>\u2022 But there is no COVID-19 vaccine yet, so plasma from recovered patients remains doctors\u2019 best source of antibodies for now.<\/p>\n\n\n\n<p><strong>What is the process?<\/strong><\/p>\n\n\n\n<p>1. To get the plasma, people who have fully recovered from the infection must first donate blood. Donors must be free of symptoms for at least 14 days.<\/p>\n\n\n\n<p>2. The plasma is then separated from the blood in a process called plasmapheresis and screened for toxins or infections, like hepatitis or HIV. Next, the plasma is tested to make sure it has enough antibodies to effectively treat or prevent COVID-19.<\/p>\n\n\n\n<p>3. After that, it can be infused into the recipient through a procedure that\u2019s similar to a blood transfusion and is known to be safe.<\/p>\n\n\n\n<p><strong>Is this \u2018THE CURE\u2019 for COVID19?<\/strong><\/p>\n\n\n\n<p>1. Convalescent plasma is a stopgap measure until a better treatment or vaccine is available.<\/p>\n\n\n\n<p>2. The therapy will be useful for people who have been hospitalized with COVID-19 but are not yet in critical condition.<\/p>\n\n\n\n<p>3. If the treatment can prevent those people from ending up in the intensive care unit, it will free up valuable resources like beds and ventilators for patients with more severe illness.<\/p>\n\n\n\n<p><strong>Challenges-<\/strong><\/p>\n\n\n\n<p>One of the challenges of plasma therapy will be administering it in the&nbsp;<strong>right window of time&nbsp;<\/strong>to provide the maximum boost to a person\u2019s immune system.<\/p>\n\n\n\n<p>The sooner it can be given (ideally, within a few days after exposure or the onset of symptoms), the better a person will likely fare.<\/p>\n\n\n\n<p>After that, patients might be too far along in the course of their disease to benefit. The<strong>&nbsp;timing could be tricky<\/strong>&nbsp;because some people aren\u2019t admitted to the hospital until many days after their illness has begun.<\/p>\n<div style=\"padding-bottom:20px; padding-top:10px;\" class=\"hupso-share-buttons\"><!-- Hupso Share Buttons - https:\/\/www.hupso.com\/share\/ --><a class=\"hupso_toolbar\" href=\"https:\/\/www.hupso.com\/share\/\"><img data-recalc-dims=\"1\" decoding=\"async\" src=\"https:\/\/i0.wp.com\/static.hupso.com\/share\/buttons\/share-medium.png?w=640&#038;ssl=1\" style=\"border:0px; padding-top:5px; float:left;\" alt=\"Share Button\"\/><\/a><script type=\"text\/javascript\">var hupso_services_t=new Array(\"Twitter\",\"Facebook\",\"Pinterest\",\"Linkedin\");var hupso_background_t=\"#EAF4FF\";var hupso_border_t=\"#66CCFF\";var hupso_toolbar_size_t=\"medium\";var hupso_twitter_via = \"datebytype\";var hupso_image_folder_url = \"\";var hupso_twitter_via=\"datebytype\";var hupso_url_t=\"\";var hupso_title_t=\"Can plasma from COVID-19 survivors treat others?\";<\/script><script type=\"text\/javascript\" src=\"https:\/\/static.hupso.com\/share\/js\/share_toolbar.js\"><\/script><!-- Hupso Share Buttons --><\/div>","protected":false},"excerpt":{"rendered":"<div style=\"padding-bottom:20px; padding-top:10px;\" class=\"hupso-share-buttons\"><!-- Hupso Share Buttons - https:\/\/www.hupso.com\/share\/ --><a class=\"hupso_toolbar\" href=\"https:\/\/www.hupso.com\/share\/\"><img src=\"https:\/\/static.hupso.com\/share\/buttons\/share-medium.png\" style=\"border:0px; padding-top:5px; float:left;\" alt=\"Share Button\"\/><\/a><script type=\"text\/javascript\">var hupso_services_t=new Array(\"Twitter\",\"Facebook\",\"Pinterest\",\"Linkedin\");var hupso_background_t=\"#EAF4FF\";var hupso_border_t=\"#66CCFF\";var hupso_toolbar_size_t=\"medium\";var hupso_twitter_via = \"datebytype\";var hupso_image_folder_url = \"\";var hupso_twitter_via=\"datebytype\";var hupso_url_t=\"\";var hupso_title_t=\"Can plasma from COVID-19 survivors treat others?\";<\/script><script type=\"text\/javascript\" src=\"https:\/\/static.hupso.com\/share\/js\/share_toolbar.js\"><\/script><!-- Hupso Share Buttons --><\/div>This question has come up a lot lately. Is hyperimmune plasma therapy effective? Hyperimmune serum is blood plasma containing high amounts of an antibody. It has been hypothesised that hyperimmune serum may be an effective therapy for persons infected with the Ebola virus. Another study identified 32 studies of SARS coronavirus infection and severe influenza and concluded the following: Available evidence suggests that convalescent plasma is likely to reduce mortality during SARIs of viral etiology, with larger treatment effects if it commenced early after symptom onset. However, this is based on predominately low-quality, uncontrolled studies. Our review supports the use of&nbsp; convalescent plasma in critically ill MERS-CoV\u2013infected patients as part of a well-designed clinical trial or other formal evaluation. Here <div style=\"padding-bottom:20px; padding-top:10px;\" class=\"hupso-share-buttons\"><!-- Hupso Share Buttons - https:\/\/www.hupso.com\/share\/ --><a class=\"hupso_toolbar\" href=\"https:\/\/www.hupso.com\/share\/\"><img src=\"https:\/\/static.hupso.com\/share\/buttons\/share-medium.png\" style=\"border:0px; padding-top:5px; float:left;\" alt=\"Share Button\"\/><\/a><script type=\"text\/javascript\">var hupso_services_t=new Array(\"Twitter\",\"Facebook\",\"Pinterest\",\"Linkedin\");var hupso_background_t=\"#EAF4FF\";var hupso_border_t=\"#66CCFF\";var hupso_toolbar_size_t=\"medium\";var hupso_twitter_via = \"datebytype\";var hupso_image_folder_url = \"\";var hupso_twitter_via=\"datebytype\";var hupso_url_t=\"\";var hupso_title_t=\"Can plasma from COVID-19 survivors treat others?\";<\/script><script type=\"text\/javascript\" src=\"https:\/\/static.hupso.com\/share\/js\/share_toolbar.js\"><\/script><!-- Hupso Share Buttons --><\/div>","protected":false},"author":1,"featured_media":7471,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"amp_status":"","_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","enabled":false},"version":2}},"categories":[1],"tags":[],"class_list":["post-7470","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-facts"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"https:\/\/i0.wp.com\/www.rhesusnegative.net\/staynegative\/wp-content\/uploads\/2020\/04\/EV2HyHAWkAocACA.jpg?fit=679%2C390&ssl=1","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p5DV68-1Wu","_links":{"self":[{"href":"https:\/\/www.rhesusnegative.net\/staynegative\/wp-json\/wp\/v2\/posts\/7470","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.rhesusnegative.net\/staynegative\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.rhesusnegative.net\/staynegative\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.rhesusnegative.net\/staynegative\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.rhesusnegative.net\/staynegative\/wp-json\/wp\/v2\/comments?post=7470"}],"version-history":[{"count":5,"href":"https:\/\/www.rhesusnegative.net\/staynegative\/wp-json\/wp\/v2\/posts\/7470\/revisions"}],"predecessor-version":[{"id":7485,"href":"https:\/\/www.rhesusnegative.net\/staynegative\/wp-json\/wp\/v2\/posts\/7470\/revisions\/7485"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.rhesusnegative.net\/staynegative\/wp-json\/wp\/v2\/media\/7471"}],"wp:attachment":[{"href":"https:\/\/www.rhesusnegative.net\/staynegative\/wp-json\/wp\/v2\/media?parent=7470"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.rhesusnegative.net\/staynegative\/wp-json\/wp\/v2\/categories?post=7470"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.rhesusnegative.net\/staynegative\/wp-json\/wp\/v2\/tags?post=7470"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}