{"id":9158,"date":"2020-11-26T17:41:09","date_gmt":"2020-11-26T17:41:09","guid":{"rendered":"https:\/\/www.rhesusnegative.net\/staynegative\/?p=9158"},"modified":"2022-03-31T23:46:30","modified_gmt":"2022-03-31T23:46:30","slug":"why-are-there-no-neanderthal-mtdna-haplogroups-present-in-modern-humans","status":"publish","type":"post","link":"https:\/\/www.rhesusnegative.net\/staynegative\/why-are-there-no-neanderthal-mtdna-haplogroups-present-in-modern-humans\/","title":{"rendered":"&#8220;Why are there no Neanderthal mtDNA haplogroups present in modern humans?&#8221;"},"content":{"rendered":"<div style=\"padding-bottom:20px; padding-top:10px;\" class=\"hupso-share-buttons\"><!-- Hupso Share Buttons - https:\/\/www.hupso.com\/share\/ --><a class=\"hupso_toolbar\" href=\"https:\/\/www.hupso.com\/share\/\"><img data-recalc-dims=\"1\" decoding=\"async\" src=\"https:\/\/i0.wp.com\/static.hupso.com\/share\/buttons\/share-medium.png?w=640&#038;ssl=1\" style=\"border:0px; padding-top:5px; float:left;\" alt=\"Share Button\"\/><\/a><script type=\"text\/javascript\">var hupso_services_t=new Array(\"Twitter\",\"Facebook\",\"Pinterest\",\"Linkedin\");var hupso_background_t=\"#EAF4FF\";var hupso_border_t=\"#66CCFF\";var hupso_toolbar_size_t=\"medium\";var hupso_twitter_via = \"datebytype\";var hupso_image_folder_url = \"\";var hupso_twitter_via=\"datebytype\";var hupso_url_t=\"\";var hupso_title_t=\"&quot;Why are there no Neanderthal mtDNA haplogroups present in modern humans?&quot;\";<\/script><script type=\"text\/javascript\" src=\"https:\/\/static.hupso.com\/share\/js\/share_toolbar.js\"><\/script><!-- Hupso Share Buttons --><\/div>\n<div class=\"wp-block-image\"><figure class=\"aligncenter\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" width=\"640\" height=\"336\" src=\"https:\/\/i0.wp.com\/www.rhesusnegative.net\/staynegative\/wp-content\/uploads\/2020\/11\/worlds-oldest-cave-paintings.jpg?resize=640%2C336&#038;ssl=1\" alt=\"\" class=\"wp-image-9161\" srcset=\"https:\/\/i0.wp.com\/www.rhesusnegative.net\/staynegative\/wp-content\/uploads\/2020\/11\/worlds-oldest-cave-paintings.jpg?resize=1024%2C538&amp;ssl=1 1024w, https:\/\/i0.wp.com\/www.rhesusnegative.net\/staynegative\/wp-content\/uploads\/2020\/11\/worlds-oldest-cave-paintings.jpg?resize=300%2C158&amp;ssl=1 300w, https:\/\/i0.wp.com\/www.rhesusnegative.net\/staynegative\/wp-content\/uploads\/2020\/11\/worlds-oldest-cave-paintings.jpg?resize=768%2C403&amp;ssl=1 768w, https:\/\/i0.wp.com\/www.rhesusnegative.net\/staynegative\/wp-content\/uploads\/2020\/11\/worlds-oldest-cave-paintings.jpg?w=1200&amp;ssl=1 1200w\" sizes=\"auto, (max-width: 640px) 100vw, 640px\" \/><figcaption>Little known fact: World&#8217;s oldest cave paintings were probably made by Neanderthals<\/figcaption><\/figure><\/div>\n\n\n\n<p>This question keeps coming up. As Europeans have 2-4% Neanderthal DNA, the claims made make people wonder. The problem with the claim:<\/p>\n\n\n\n<p>It is silly.<\/p>\n\n\n\n<p>Here is why:<\/p>\n\n\n\n<p>&#8220;<strong>Neanderthal&nbsp;mtDNA&nbsp;is very different from human&nbsp;mtDNA, so interbreeding did not happen.<\/strong><br>=&gt; FALSE : this is one of the stupidest argument I have read so far. First of all, Mitochondrial DNA is only transmitted by the mother. It is very possible that some haplogroups have disappeared with time, especially if they had pathogenic mutations. If Neanderthal&nbsp;mtDNA&nbsp;caused an evolutionary handicap compared to Homo Sapiens&nbsp;mtDNA, it would have been wiped out with a few hundreds or thousands years.<\/p>\n\n\n\n<p>Take a family tree of cave person going back 5 generations. All of his 32 great-great-great-grand-parents are Homo Sapiens, except one Neanderthal woman. If the Neanderthal woman is not the ancestor in cognatic line (mother&#8217;s mother&#8217;s mother&#8217;s&#8230;), then the child will not inherit Neanderthal&nbsp;mtDNA, although he\/she will inherit other genes from Neanderthal. After 5 generations there is only one chance out of 16 to inherit that particular female ancestor&#8217;s&nbsp;mtDNA. After 21 generations, there is only one chance out of 1 million. If that&nbsp;mtDNA&nbsp;is pathogenic, the chances are close to zero. Think about 1,000 generations that separate us from the &#8220;extinction&#8221; of pure&nbsp;Neanderthals.<\/p>\n\n\n\n<p>Secondly,&nbsp;mtDNA&nbsp;evolves with time. Most of the haplogroups found in Europe nowadays did not exist 40,000 years ago, when Homo Sapiens reached Europe. If Neanderthal&nbsp;mtDNA&nbsp;had survived, it would have evolved just like Homo Sapiens&nbsp;mtDNA. If we found that&nbsp;mtDNA&nbsp;in someone, it would be quite difficult to recognise when compared to the few samples of Neanderthal bones (some over 100,000 years old !) tested. It could be that haplogroups such as X, W or I actually descend from Neanderthal, but have a high genetic distance to the bones tested because a) they do not belong to the same subspecies of Neanderthal, and b) they have evolved too much in 40,000 years. &#8220;<\/p>\n\n\n\n<p>Source and more:<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><a href=\"https:\/\/www.eupedia.com\/forum\/threads\/24893-Do-modern-Europeans-partly-descend-from-Neanderthal?highlight=neanderthals+mtdna\" target=\"_blank\" rel=\"noreferrer noopener\" aria-label=\"Do modern Europeans partly descend from Neanderthal ? (opens in a new tab)\">Do modern Europeans partly descend from Neanderthal ?<\/a><\/h2>\n\n\n\n<figure class=\"wp-block-embed-wordpress wp-block-embed is-type-wp-embed is-provider-rh-negative-blood-and-people\"><div class=\"wp-block-embed__wrapper\">\n<blockquote class=\"wp-embedded-content\" data-secret=\"jaFCK9bDeE\"><a href=\"https:\/\/www.rhesusnegative.net\/staynegative\/why-is-there-no-neanderthal-y-dna-in-modern-humans\/\">&#8220;Why is there no Neanderthal y-DNA in modern humans?&#8221;<\/a><\/blockquote><iframe loading=\"lazy\" class=\"wp-embedded-content\" sandbox=\"allow-scripts\" security=\"restricted\" style=\"position: absolute; clip: rect(1px, 1px, 1px, 1px);\" title=\"&#8220;&#8220;Why is there no Neanderthal y-DNA in modern humans?&#8221;&#8221; &#8212; The Rh Negative Blog\" src=\"https:\/\/www.rhesusnegative.net\/staynegative\/why-is-there-no-neanderthal-y-dna-in-modern-humans\/embed\/#?secret=GBqMimCmyt#?secret=jaFCK9bDeE\" data-secret=\"jaFCK9bDeE\" width=\"600\" height=\"338\" frameborder=\"0\" marginwidth=\"0\" marginheight=\"0\" scrolling=\"no\"><\/iframe>\n<\/div><\/figure>\n\n\n\n<p><ins><br>\n\n<\/ins><\/p>\n<div style=\"padding-bottom:20px; padding-top:10px;\" class=\"hupso-share-buttons\"><!-- Hupso Share Buttons - https:\/\/www.hupso.com\/share\/ --><a class=\"hupso_toolbar\" href=\"https:\/\/www.hupso.com\/share\/\"><img data-recalc-dims=\"1\" decoding=\"async\" src=\"https:\/\/i0.wp.com\/static.hupso.com\/share\/buttons\/share-medium.png?w=640&#038;ssl=1\" style=\"border:0px; padding-top:5px; float:left;\" alt=\"Share Button\"\/><\/a><script type=\"text\/javascript\">var hupso_services_t=new Array(\"Twitter\",\"Facebook\",\"Pinterest\",\"Linkedin\");var hupso_background_t=\"#EAF4FF\";var hupso_border_t=\"#66CCFF\";var hupso_toolbar_size_t=\"medium\";var hupso_twitter_via = \"datebytype\";var hupso_image_folder_url = \"\";var hupso_twitter_via=\"datebytype\";var hupso_url_t=\"\";var hupso_title_t=\"&quot;Why are there no Neanderthal mtDNA haplogroups present in modern humans?&quot;\";<\/script><script type=\"text\/javascript\" src=\"https:\/\/static.hupso.com\/share\/js\/share_toolbar.js\"><\/script><!-- Hupso Share Buttons --><\/div>","protected":false},"excerpt":{"rendered":"<div style=\"padding-bottom:20px; padding-top:10px;\" class=\"hupso-share-buttons\"><!-- Hupso Share Buttons - https:\/\/www.hupso.com\/share\/ --><a class=\"hupso_toolbar\" href=\"https:\/\/www.hupso.com\/share\/\"><img src=\"https:\/\/static.hupso.com\/share\/buttons\/share-medium.png\" style=\"border:0px; padding-top:5px; float:left;\" alt=\"Share Button\"\/><\/a><script type=\"text\/javascript\">var hupso_services_t=new Array(\"Twitter\",\"Facebook\",\"Pinterest\",\"Linkedin\");var hupso_background_t=\"#EAF4FF\";var hupso_border_t=\"#66CCFF\";var hupso_toolbar_size_t=\"medium\";var hupso_twitter_via = \"datebytype\";var hupso_image_folder_url = \"\";var hupso_twitter_via=\"datebytype\";var hupso_url_t=\"\";var hupso_title_t=\"&quot;Why are there no Neanderthal mtDNA haplogroups present in modern humans?&quot;\";<\/script><script type=\"text\/javascript\" src=\"https:\/\/static.hupso.com\/share\/js\/share_toolbar.js\"><\/script><!-- Hupso Share Buttons --><\/div>This question keeps coming up. As Europeans have 2-4% Neanderthal DNA, the claims made make people wonder. The problem with the claim: It is silly. Here is why: &#8220;Neanderthal&nbsp;mtDNA&nbsp;is very different from human&nbsp;mtDNA, so interbreeding did not happen.=&gt; FALSE : this is one of the stupidest argument I have read so far. First of all, Mitochondrial DNA is only transmitted by the mother. It is very possible that some haplogroups have disappeared with time, especially if they had pathogenic mutations. If Neanderthal&nbsp;mtDNA&nbsp;caused an evolutionary handicap compared to Homo Sapiens&nbsp;mtDNA, it would have been wiped out with a few hundreds or thousands years. Take a family tree of cave person going back 5 generations. All of his 32 great-great-great-grand-parents are Homo <div style=\"padding-bottom:20px; padding-top:10px;\" class=\"hupso-share-buttons\"><!-- Hupso Share Buttons - https:\/\/www.hupso.com\/share\/ --><a class=\"hupso_toolbar\" href=\"https:\/\/www.hupso.com\/share\/\"><img src=\"https:\/\/static.hupso.com\/share\/buttons\/share-medium.png\" style=\"border:0px; padding-top:5px; float:left;\" alt=\"Share Button\"\/><\/a><script type=\"text\/javascript\">var hupso_services_t=new Array(\"Twitter\",\"Facebook\",\"Pinterest\",\"Linkedin\");var hupso_background_t=\"#EAF4FF\";var hupso_border_t=\"#66CCFF\";var hupso_toolbar_size_t=\"medium\";var hupso_twitter_via = \"datebytype\";var hupso_image_folder_url = \"\";var hupso_twitter_via=\"datebytype\";var hupso_url_t=\"\";var hupso_title_t=\"&quot;Why are there no Neanderthal mtDNA haplogroups present in modern humans?&quot;\";<\/script><script type=\"text\/javascript\" src=\"https:\/\/static.hupso.com\/share\/js\/share_toolbar.js\"><\/script><!-- Hupso Share Buttons --><\/div>","protected":false},"author":1,"featured_media":9161,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"amp_status":"","_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","enabled":false},"version":2}},"categories":[1],"tags":[],"class_list":["post-9158","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-facts"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"https:\/\/i0.wp.com\/www.rhesusnegative.net\/staynegative\/wp-content\/uploads\/2020\/11\/worlds-oldest-cave-paintings.jpg?fit=1200%2C630&ssl=1","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p5DV68-2nI","_links":{"self":[{"href":"https:\/\/www.rhesusnegative.net\/staynegative\/wp-json\/wp\/v2\/posts\/9158","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.rhesusnegative.net\/staynegative\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.rhesusnegative.net\/staynegative\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.rhesusnegative.net\/staynegative\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.rhesusnegative.net\/staynegative\/wp-json\/wp\/v2\/comments?post=9158"}],"version-history":[{"count":4,"href":"https:\/\/www.rhesusnegative.net\/staynegative\/wp-json\/wp\/v2\/posts\/9158\/revisions"}],"predecessor-version":[{"id":13096,"href":"https:\/\/www.rhesusnegative.net\/staynegative\/wp-json\/wp\/v2\/posts\/9158\/revisions\/13096"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.rhesusnegative.net\/staynegative\/wp-json\/wp\/v2\/media\/9161"}],"wp:attachment":[{"href":"https:\/\/www.rhesusnegative.net\/staynegative\/wp-json\/wp\/v2\/media?parent=9158"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.rhesusnegative.net\/staynegative\/wp-json\/wp\/v2\/categories?post=9158"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.rhesusnegative.net\/staynegative\/wp-json\/wp\/v2\/tags?post=9158"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}