Is there any Relationship between Rh(D) Blood Group and Von Willebrand Factor Antigen Concentration?

This study has shown that plasma vWF:Ag levels in healthy Nigerian subjects vary widely. It is also evident from this work that ABO blood group but not Rh(D) blood group has a significant influence on plasma vWF:Ag levels and needs to be taken into cognizance when establishing reference range for vWF:Ag. However, we recommend that further studies including community – based survey with larger sample size should be conducted in other parts of the world to determine the relationship between the Rh blood group in general and plasma vWF:Ag concentration for the purpose of validating the present observation. It is hoped that this work will form the basis for a more extensive prospective study in the nearest future.

https://www.cosmosscholars.com/images/GJHBT_-_V3N2/GJHBT-V3N2A3-Akpan.pdf

Von Willebrand disease low among people with blood type O