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Testing the association between blood type and COVID-19 infection, intubation, and death

Testing the association between blood type and COVID-19 infection, intubation, and death

 Rhesusnegative.net12
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The following information is from the latest, Sept. 10th 2020, revision of the study I have already posted in May.

The rapid global spread of the novel coronavirus SARS-CoV-2 has strained healthcare and testing resources, making the identification and prioritization of individuals most at-risk a critical challenge. Recent evidence suggests blood type may affect risk of severe COVID-19. We used observational healthcare data on 14,112 individuals tested for SARS-CoV-2 with known blood type in the New York Presbyterian (NYP) hospital system to assess the association between ABO and Rh blood types and infection, intubation, and death. We found slightly increased infection prevalence among non-O types. Risk of intubation was decreased among A and increased among AB and B types, compared with type O, while risk of death was increased for type AB and decreased for types A and B. We estimated Rh-negative blood type to have a protective effect for all three outcomes. Our results add to the growing body of evidence suggesting blood type may play a role in COVID-19.

https://www.medrxiv.org/content/10.1101/2020.04.08.20058073v3
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7276013/
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12 Comments

  1. Cathryn September 19, 2020

    I always read and enjoy your posts.
    Thank you Micheal.

  2. Richard Youatt September 20, 2020

    Mike:

    This is a very substantive and statistically significant study that strongly supports your primary arguments.

    Intuitive reasoning makes me think that there must be some type of link to work on the function and nature of RH proteins.

    At the personal level, it is interesting to me since my grandson was born in New York Presbyterian Hospital. His mom was/is RH negative.

    Richard

  3. moira September 21, 2020

    reading this … great information

  4. Alice October 1, 2020

    Thank You for all your intresting articles in general and great work with Covid analysis for exemple. I’ve red your blog for 10 year !

  5. Paul October 15, 2020

    First review

    Reviewed by Miriam Saffern as part of a project by students, postdocs and faculty at the Immunology Institute of the Icahn School of Medicine, Mount Sinai.

    “ Furthermore, the analyses that included Rh factor, the sample sizes for all Rh-negative subtypes were also small, and there were no patients with AB-negative blood who tested positive for the virus. This highlights the necessity for larger cohorts from multiple sites, but the preliminary results are promising.”

    https://disqus.com/by/sinaiimmunologyreviewproject/

  6. Paul October 19, 2020

    Another interesting Turkish study published on 21st September 2020, though a relatively small study of 397 patients it did include statistics on RH – patients (roughly 10% were RH-)

    When referring to tables 1 & 2, it appears that all of the patients that were admitted into ICU were RH + (none were RH -) and those who unfortunately passed away were also all RH + (none RH -).

    https://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302020001400086&fbclid=IwAR214S732Uaq-peNDcPAJWa8S4jKB5_xp7lNH5MQNH32V3-IlRCNQV_JoIU

    • Paul October 19, 2020

      Sorry, correction I was referring to Table 1 & 3.

  7. Jayne Bogdajewicz January 28, 2021

    I am AB negative and have been recently interested on how the RH negative blood type reacts to illness. I am very healthy and rarely, if ever get sick (60 years old). During covid I have been around hundreds of people, and maskless I might add, and have yet to get sick. It seems that RH negative blood may have a protective factor, or maybe I am just lucky!

    • mizar March 17, 2021

      I must worry about people with a group of blood RH Negative are not protected from this virus. With us in Poland there are quite a lot of people with this group of blood and they also suffer from Cowid-19. All these studies are not reliable and give unnecessary hope from RH Negative.

  8. Kela Parker March 5, 2021

    it seems to me that if Rh – blood is significantly less common in the overall population, and we’re talking about a brand new virus that is rapidly evolving and about which very few studies are done, and in those studies some Rh – types were not even showing as positive for Covid 19 in the first place (as indicated above), it is far too early to draw any conclusions about Rh – being protective once the virus has been contracted.

    Concluding there is a positive correlation between Rh – blood and less likelihood of infection and/or negative longterm reaction when there are simply less of us in the population, and therefore less of us in clinical trials and hospitalizations overall no matter what, is like doing a survey in a community to determine how many people like driving red cars, in a place where there aren’t many people that own cars to begin with, and concluding that red cars aren’t popular. It’s a false correlation.

  9. jayne travis May 26, 2021

    fascinating read…i am a rhesus negative

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