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Evidence that Rh (Rhesus) proteins are CO2 channels

Evidence that Rh (Rhesus) proteins are CO2 channels

 Rhesusnegative.net6
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Twenty thousand years ago, when humans were still nomadic hunters and gatherers, low concentrations of carbon dioxide in the atmosphere likely made the earth a much better environment for rh negatives. Why?
CO2 is being transported via rh proteins meaning it is tougher for rh negatives to get rid of.

This study is from 2006:

Physiological evidence from our laboratory indicates that Amt/Mep proteins are gas channels for NH3, the first biological gas channels to be described. This view has now been confirmed by structural evidence and is displacing the previous belief that Amt/Mep proteins were active transporters for the NH4+ ion. Still disputed is the physiological substrate for Rh proteins, the only known homologues of Amt/Mep proteins. Many think they are mammalian ammonium (NH4+ or NH3) transporters. Following Monod’s famous dictum, “Anything found to be true of E. coli must also be true of elephants” [Perspect. Biol. Med. 47(1) (2004) 47], we explored the substrate for Rh proteins in the unicellular green alga Chlamydomonas reinhardtii. C. reinhardtii is one of the simplest organisms to have Rh proteins and it also has Amt proteins. Physiological studies in this microbe indicate that the substrate for Rh proteins is CO2 and confirm that the substrate for Amt proteins is NH3. Both are readily hydrated gases. Knowing that transport of CO2 is the ancestral function of Rh proteins supports the inference from hematological research that a newly evolving role of the human Rh30 proteins, RhCcEe and RhD, is to help maintain the flexible, flattened shape of the red cell.

Source: Biological gas channels for NH3 and CO2: evidence that Rh (Rhesus) proteins are CO2 channels.

Where do rh negatives feel most comfortable and why?

These days, it is likely the case that overall, rh negatives are best suited for environments with either low CO2 levels or simply high oxygen levels. Which would likely reduce us to lower elevations, if possible surrounded by nature and close to the ocean or a large sea (e.g. Black Sea).

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Rhesusnegative.net

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6 Comments

  1. Kellie October 5, 2018

    So THIS is why i burp from anything and everything, even a drink of water?!?!
    I have been mocked my whole life for excessive belching, but i had no idea there was a basis for my constant issue! thank you once again Mike, for providing valuable info!

    • Cynthia October 7, 2018

      I have always had a burping problem too. And I am happy to know I belong near the sea…now if only I could afford to live there.
      A Negative

  2. Fernando October 6, 2018

    Salve, leggendo questo interessante post, mi chiedo:
    Tutto questo, potrebbe rappresentare anche un vantaggio per gli Rh- negativi non accumulare la CO2 nei tessuti? Non riuscendola a trasportare efficacemente con i propri globuli rossi, vuol dire anche non accumularla ovunque… e per me non è una cosa cattiva o uno svantaggio.
    Ciao from Italy

    • Mike DammannAuthor October 8, 2018

      Niente di tutto ciò è negativo. Significa solo che dovremmo vivere vicino all’oceano, non in alta quota ed essere il più vicino possibile alla natura (senza scarico).

  3. lauren October 17, 2018

    Is that why my Rh- mom was a mosquito magnet?

  4. Valerie Cuan October 31, 2018

    I don’t understand what all that means to us but i can say my blood was analyzed and the shape wasn’t considered normal or healthy. That was because of toxins, viruses or whatever but maybe ours is a different shape anyway.

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