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Relationship between blood type and outcomes following COVID-19 infection

Relationship between blood type and outcomes following COVID-19 infection

 Rhesusnegative.net4
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What are your thoughts on this study?

Since the onset of the COVID-19 pandemic, a concentrated research effort has been undertaken to elucidate risk factors underlying viral susceptibility and illness. Among these efforts, several recent studies have investigated the association between blood type and COVID-19 infection. Each of these reports provides important information with regard to understanding the underlying disease process. Although these reports might be inconsistent in their findings, certain trends are evident. Many studies report that blood type A might predispose one to increased susceptibility of infection with SARS-CoV-2, and type O and Rh-negative blood groups might be protective. Although this appears to be an emerging trend, the impact of blood type on clinical outcomes remains unclear. At this point in time, there does not appear to be any relationship between blood type and COVID-19–related severity of illness or mortality. Current literature does not support blood type as part of a predictive model of viral illness or mortality, and ABO/Rh screening should not be used as a triage mechanism. Future investigations can focus on the creation of a global COVID-19 database to account for population-based differences in blood types and testing protocols. In addition, further studies are necessary to understand the molecular mechanisms by which blood types might engender susceptibility to SARS-CoV-2 infection, and ultimately, develop countermeasures to viral infection and illness.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8286549/

Why is the outcome so different from the others I have highlighted?

Impact of ABO and Rhesus blood groups on COVID-19 susceptibility and severity: A case-control study

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Rhesusnegative.net

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4 Comments

  1. Jessica January 9, 2022

    In my case, O blood seems to have given my daughter (she’s O+ and I’m O-) an advantage because when my family got what I’m sure was covid, we were the only two who didn’t. No one else is an O blood type. My other kids have a different dad.

  2. Richard Youatt January 9, 2022

    This is a well designed and well conducted study that should not be ignored ! It is also easy to read. At the personal level, my spouse is A Rh + and I am B Rh neg. We had similar exposure to a person who was positive for COVID19. Antigen tests on my spouse were positive and she had mild symptoms. I tested negative and had no symptoms. Statistical sample is too small to generalize, but I agree 100% that more focused research on the genetic mechanisms is imperative.

  3. JB January 11, 2022

    Exposed on New Year’s Eve at work.. exposed by 4 more people for 4 hours maskeless in a small space the following Monday. My exposures were all vaccinated and positive. I am unvaccinated and O- and have tested negative twice since exposure. I know of 10 positive cases that have come from the same exposure that I had. I have pre-existing auto-immune conditions and have been very worried due to being exposed. I was shocked today after my second test to find out I tested negative.

  4. Tami February 15, 2022

    Haven’t had covid and made the personal choice not to receive the vaccine. I’m O- and 62 years old.

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